Basic Information
Symbol
circCCDC40
RNA Class
circRNA
Alias
Coiled-Coil Domain 40 Molecular Ruler Complex Subunit
KIAA1640
CFAP172
CILD15
FAP172
Coiled-Coil Domain-Containing Protein 40
Coiled-Coil Domain Containing 40
FLJ20753
FLJ32021
Location (GRCh37)
17:78022382-78024082
UCSC Genome Browser
Location (GRCh38)
17:80048583-80050283
Host gene
CCDC40
Host category
mRNA
Forensic tag(s)
Tissue/body fluid identification
Mixture deconvolution
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_CCDC40_0001600 | Exon-Exon | chr17:78022382-78024082 | chr17:80048583-80050283 | 483 nt | 0.6211 |
Forensic Context
A study in humans demonstrated that the circCCDC40 is a highly specific circular RNA marker for semen identification, as part of a target RNA sequencing panel developed for body fluid contributor deconvolution in forensic mixtures [Yu et al. DOI:10.1016/j.fsigen.2025.103416]. The assay, which included 135 RNA-SNPs across 42 body fluid genes, showed clear separation between five body fluid types in single-source samples and successfully detected all components in artificial mixtures of 2–5 body fluids, with most genotypes correctly associated with their contributors.