Basic Information

Symbol
circCCNB1
RNA Class
circRNA
Alias
Cyclin B1 CCNB G2/Mitotic-Specific Cyclin-B1 G2/Mitotic-Specific Cyclin B1
Location (GRCh37)
5:68411064-68474070 UCSC Genome Browser
Location (GRCh38)
5:69115237-69178243
UCSC Genome Browser Search in Marker Scope
Host gene
CCNB1
Host category
mRNA
Forensic tag(s)
Chronological age estimation
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CCNB1_0000300 Exon-Exon chr5:68463020-68471364 chr5:69167193-69175537 1153 nt 0.4623
hsa_CCNB1_0000700 Exon-Exon chr5:68467097-68467279 chr5:69171270-69171452 183 nt 0.4262
hsa_CCNB1_0000800 Exon-Exon chr5:68467097-68470236 chr5:69171270-69174409 342 nt 0.4386
hsa_CCNB1_0000900 Exon-Exon chr5:68467097-68471364 chr5:69171270-69175537 720 nt 0.4292
hsa_CCNB1_0001200 Exon-Exon chr5:68470078-68470236 chr5:69174251-69174409 159 nt 0.4528
hsa_CCNB1_0001300 Exon-Exon chr5:68470078-68471364 chr5:69174251-69175537 537 nt 0.4302
hsa_CCNB1_0001500 Exon-Exon chr5:68470704-68470940 chr5:69174877-69175113 237 nt 0.4219
hsa_CCNB1_0001600 Exon-Exon chr5:68470704-68471364 chr5:69174877-69175537 378 nt 0.4206
hsa_CCNB1_0001700 Exon-Exon chr5:68470704-68473176 chr5:69174877-69177349 489 nt 0.4151
hsa_CCNB1_0001800 Exon-Exon chr5:68470704-68474070 chr5:69174877-69178243 1209 nt 0.3714
Showing 1 to 10 of 23 entries
Forensic Context

A study in humans demonstrated that the circCCNB1 can serve as a biomarker for forensic age prediction, where its expression was analyzed in peripheral blood samples from 100 individuals aged 19-73 years [Wang et al. DOI:10.3389/fgene.2022.825443]. Furthermore, a separate review highlighted that the circCCNB1 interacts with CCNB1 and CDK1 proteins, dissociating the CCNB1/CDK1 complex and resulting in a loss-of-function effect on tumorigenesis [Misir et al. DOI:10.1038/s41418-022-00948-7].