Basic Information

Symbol
circCCNB1
RNA Class
circRNA
Alias
Cyclin B1 CCNB G2/Mitotic-Specific Cyclin-B1 G2/Mitotic-Specific Cyclin B1
Location (GRCh37)
5:68411064-68474070 UCSC Genome Browser
Location (GRCh38)
5:69115237-69178243
UCSC Genome Browser Search in Marker Scope
Host gene
CCNB1
Host category
mRNA
Forensic tag(s)
Chronological age estimation
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CCNB1_0002000 Exon-Exon chr5:68471224-68471364 chr5:69175397-69175537 141 nt 0.4184
hsa_SLC30A5_0006000 Exon-Intergenic chr5:68411064-68471364 chr5:69115237-69175537 250 nt 0.3400
hsa_snoU13_0006800 Intergenic-Exon-Intergenic chr5:68467157-68473086 chr5:69171330-69177259 681 nt 0.4200
hsa_CCNB1_0000200 Intergenic-Exon chr5:68452358-68471364 chr5:69156531-69175537 141 nt 0.4184
hsa_CCNB1_0000400 Exon-Exon chr5:68463084-68463905 chr5:69167257-69168078 198 nt 0.5253
hsa_CCNB1_0000500 Exon-Exon chr5:68463735-68463905 chr5:69167908-69168078 171 nt 0.5029
hsa_CCNB1_0000600 Exon-Exon chr5:68463735-68467279 chr5:69167908-69171452 183 nt 0.4262
hsa_CCNB1_0001000 Exon-Exon chr5:68467097-68470181 chr5:69171270-69174354 287 nt 0.4355
hsa_CCNB1_0001100 Exon-Exon chr5:68467097-68473176 chr5:69171270-69177349 831 nt 0.4248
hsa_chr5_0564600 Intergenic-Intergenic chr5:68467229-68470872 chr5:69171402-69175045 51 nt 0.3137
Showing 11 to 20 of 23 entries
Forensic Context

A study in humans demonstrated that the circCCNB1 can serve as a biomarker for forensic age prediction, where its expression was analyzed in peripheral blood samples from 100 individuals aged 19-73 years [Wang et al. DOI:10.3389/fgene.2022.825443]. Furthermore, a separate review highlighted that the circCCNB1 interacts with CCNB1 and CDK1 proteins, dissociating the CCNB1/CDK1 complex and resulting in a loss-of-function effect on tumorigenesis [Misir et al. DOI:10.1038/s41418-022-00948-7].