Basic Information

Symbol
circCDYL
RNA Class
circRNA
Alias
Chromodomain Y Like CDYL1 Testis-Specific Chromodomain Y-Like Protein Chromodomain Protein, Y-Like Chromodomain Y-Like Protein Crotonyl-CoA Hydratase CDY-Like, Autosomal DKFZP586C1622 Chromodomain Protein, Y Chromosome-Like EC 2.3.1.48 EC 4.2.1.- CDY-Like
Location (GRCh37)
6:4706393-4955778 UCSC Genome Browser
Location (GRCh38)
Host gene
CDYL
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CDYL_0000100 Exon-Exon chr6:4706393-4892613 chr6:4706159-4892379 984 nt 0.5325
hsa_CDYL_0000300 Exon-Exon chr6:4715975-4892613 chr6:4715741-4892379 891 nt 0.5387
hsa_CDYL_0001000 Exon-Exon chr6:4836332-4892613 chr6:4836098-4892379 878 nt 0.5262
hsa_CDYL_0004300 Exon-Exon chr6:4890226-4892613 chr6:4889992-4892379 802 nt 0.5349
hsa_CDYL_0005200 Exon-Exon chr6:4891947-4892613 chr6:4891713-4892379 667 nt 0.5412
hsa_CDYL_0005300 Exon-Exon chr6:4891947-4936005 chr6:4891713-4935771 924 nt 0.5152
hsa_CDYL_0005400 Exon-Exon chr6:4891947-4937919 chr6:4891713-4937685 1045 nt 0.5148
hsa_CDYL_0005500 Exon-Exon chr6:4891947-4937971 chr6:4891713-4937737 1097 nt 0.5105
hsa_CDYL_0009600 Exon-Exon chr6:4935749-4937971 chr6:4935515-4937737 430 nt 0.4628
hsa_CDYL_0010600 Exon-Exon chr6:4954132-4955778 chr6:4953898-4955544 1647 nt 0.3843
Showing 1 to 10 of 115 entries
Forensic Context

A study in humans demonstrated that the circCDYL is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer [Misir et al. DOI:10.1038/s41418-022-00948-7]. In hepatocellular carcinoma, it promotes stem-like characteristics and tumor growth via the miR-328-3p/HIF1AN axis under hypoxic conditions [Huang et al. DOI:10.3390/cells11091381]. A study in mice demonstrated that the circCDYL is decreased in myocardial tissues and hypoxia myocardial cells, where it improves cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].