Basic Information

Symbol
circCDYL
RNA Class
circRNA
Alias
Chromodomain Y Like CDYL1 Testis-Specific Chromodomain Y-Like Protein Chromodomain Protein, Y-Like Chromodomain Y-Like Protein Crotonyl-CoA Hydratase CDY-Like, Autosomal DKFZP586C1622 Chromodomain Protein, Y Chromosome-Like EC 2.3.1.48 EC 4.2.1.- CDY-Like
Location (GRCh37)
6:4706393-4955778 UCSC Genome Browser
Location (GRCh38)
6:4706159-4955544
UCSC Genome Browser Search in Marker Scope
Host gene
CDYL
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CDYL_0010000 Intron-Exon-Intron chr6:4935749-4939356 chr6:4935515-4939122 225 nt 0.4533
hsa_CDYL_0010100 Exon-Exon chr6:4935749-4943990 chr6:4935515-4943756 211 nt 0.4360
hsa_CDYL_0010300 Exon-Exon chr6:4935815-4943990 chr6:4935581-4943756 575 nt 0.4557
hsa_CDYL_0010400 Intron-Intron chr6:4936462-4937714 chr6:4936228-4937480 1253 nt 0.4142
hsa_CDYL_0010500 Exon-Exon chr6:4937799-4952643 chr6:4937565-4952409 528 nt 0.4924
Showing 111 to 115 of 115 entries
Forensic Context

A study in humans demonstrated that the circCDYL is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer [Misir et al. DOI:10.1038/s41418-022-00948-7]. In hepatocellular carcinoma, it promotes stem-like characteristics and tumor growth via the miR-328-3p/HIF1AN axis under hypoxic conditions [Huang et al. DOI:10.3390/cells11091381]. A study in mice demonstrated that the circCDYL is decreased in myocardial tissues and hypoxia myocardial cells, where it improves cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].