Basic Information

Symbol
circCDYL
RNA Class
circRNA
Alias
Chromodomain Y Like CDYL1 Testis-Specific Chromodomain Y-Like Protein Chromodomain Protein, Y-Like Chromodomain Y-Like Protein Crotonyl-CoA Hydratase CDY-Like, Autosomal DKFZP586C1622 Chromodomain Protein, Y Chromosome-Like EC 2.3.1.48 EC 4.2.1.- CDY-Like
Location (GRCh37)
6:4706393-4955778 UCSC Genome Browser
Location (GRCh38)
Host gene
CDYL
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_chr6_0546400 Intergenic-Intergenic chr6:4713014-4718828 chr6:4712780-4718594 250 nt 0.3960
hsa_CDYL_0000200 Intron-Exon-Intron chr6:4715458-4716115 chr6:4715224-4715881 658 nt 0.4103
hsa_chr6_0546500 Intergenic-Intergenic chr6:4717002-4718828 chr6:4716768-4718594 359 nt 0.5014
hsa_chr6_0546600 Intergenic-Intergenic chr6:4717568-4718828 chr6:4717334-4718594 196 nt 0.5153
hsa_chr6_0546700 Intergenic-Intergenic chr6:4718761-4726758 chr6:4718527-4726524 68 nt 0.5147
hsa_CDYL_0000400 Intron-Intron chr6:4786822-4787963 chr6:4786588-4787729 1142 nt 0.4781
hsa_CDYL_0000500 Intron-Intron chr6:4793947-4794498 chr6:4793713-4794264 552 nt 0.4656
hsa_CDYL_0000600 Intron-Intron chr6:4814195-4817526 chr6:4813961-4817292 250 nt 0.3840
hsa_chr6_0550300 Intergenic-Intergenic chr6:4817207-4817456 chr6:4816973-4817222 250 nt 0.3680
hsa_CDYL_0000700 Intron-Intron chr6:4817389-4817787 chr6:4817155-4817553 399 nt 0.4160
Showing 11 to 20 of 115 entries
Forensic Context

A study in humans demonstrated that the circCDYL is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer [Misir et al. DOI:10.1038/s41418-022-00948-7]. In hepatocellular carcinoma, it promotes stem-like characteristics and tumor growth via the miR-328-3p/HIF1AN axis under hypoxic conditions [Huang et al. DOI:10.3390/cells11091381]. A study in mice demonstrated that the circCDYL is decreased in myocardial tissues and hypoxia myocardial cells, where it improves cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].