Basic Information

Symbol
circCDYL
RNA Class
circRNA
Alias
Chromodomain Y Like CDYL1 Testis-Specific Chromodomain Y-Like Protein Chromodomain Protein, Y-Like Chromodomain Y-Like Protein Crotonyl-CoA Hydratase CDY-Like, Autosomal DKFZP586C1622 Chromodomain Protein, Y Chromosome-Like EC 2.3.1.48 EC 4.2.1.- CDY-Like
Location (GRCh37)
6:4706393-4955778 UCSC Genome Browser
Location (GRCh38)
Host gene
CDYL
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CDYL_0000800 Intron-Exon chr6:4817513-4892337 chr6:4817279-4892103 391 nt 0.4859
hsa_CDYL_0000900 Intron-Exon-Intron chr6:4820861-4892613 chr6:4820627-4892379 250 nt 0.4160
hsa_CDYL_0001100 Exon-Intron chr6:4836351-4839063 chr6:4836117-4838829 118 nt 0.5932
hsa_CDYL_0001200 Exon-Intron chr6:4836351-4867670 chr6:4836117-4867436 192 nt 0.4688
hsa_CDYL_0001300 Exon-Exon chr6:4836351-4892613 chr6:4836117-4892379 192 nt 0.4688
hsa_CDYL_0001400 Intron-Exon-Intron chr6:4838946-4892613 chr6:4838712-4892379 250 nt 0.5000
hsa_CDYL_0001500 Intron-Intron chr6:4846056-4867670 chr6:4845822-4867436 81 nt 0.3951
hsa_CDYL_0001600 Intron-Intron chr6:4853630-4858846 chr6:4853396-4858612 250 nt 0.4560
hsa_CDYL_0001800 Intron-Intron chr6:4854759-4864555 chr6:4854525-4864321 409 nt 0.3985
hsa_CDYL_0001700 Intron-Intron chr6:4854759-4867670 chr6:4854525-4867436 250 nt 0.3200
Showing 21 to 30 of 115 entries
Forensic Context

A study in humans demonstrated that the circCDYL is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer [Misir et al. DOI:10.1038/s41418-022-00948-7]. In hepatocellular carcinoma, it promotes stem-like characteristics and tumor growth via the miR-328-3p/HIF1AN axis under hypoxic conditions [Huang et al. DOI:10.3390/cells11091381]. A study in mice demonstrated that the circCDYL is decreased in myocardial tissues and hypoxia myocardial cells, where it improves cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].