Basic Information

Symbol
circCDYL
RNA Class
circRNA
Alias
Chromodomain Y Like CDYL1 Testis-Specific Chromodomain Y-Like Protein Chromodomain Protein, Y-Like Chromodomain Y-Like Protein Crotonyl-CoA Hydratase CDY-Like, Autosomal DKFZP586C1622 Chromodomain Protein, Y Chromosome-Like EC 2.3.1.48 EC 4.2.1.- CDY-Like
Location (GRCh37)
6:4706393-4955778 UCSC Genome Browser
Location (GRCh38)
6:4706159-4955544
UCSC Genome Browser Search in Marker Scope
Host gene
CDYL
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CDYL_0001900 Intron-Exon-Intron chr6:4854759-4892613 chr6:4854525-4892379 172 nt 0.4709
hsa_CDYL_0002000 Intron-Exon-Intron chr6:4854759-4912360 chr6:4854525-4912126 115 nt 0.3391
hsa_CDYL_0002100 Intron-Intron chr6:4854806-4867670 chr6:4854572-4867436 125 nt 0.4720
hsa_CDYL_0002200 Intron-Exon-Intron chr6:4854806-4892613 chr6:4854572-4892379 125 nt 0.4720
hsa_CDYL_0002300 Intron-Exon-Intron chr6:4854806-4943990 chr6:4854572-4943756 211 nt 0.4360
hsa_CDYL_0002400 Intron-Intron chr6:4858045-4865214 chr6:4857811-4864980 250 nt 0.2840
hsa_CDYL_0002500 Intron-Exon-Intron chr6:4860319-4892613 chr6:4860085-4892379 250 nt 0.4800
hsa_CDYL_0002700 Intron-Intron chr6:4864319-4867670 chr6:4864085-4867436 480 nt 0.3500
hsa_CDYL_0002600 Intron-Exon chr6:4864319-4892337 chr6:4864085-4892103 250 nt 0.3360
hsa_CDYL_0002800 Intron-Exon-Intron chr6:4864319-4892613 chr6:4864085-4892379 81 nt 0.3951
Showing 31 to 40 of 115 entries
Forensic Context

A study in humans demonstrated that the circCDYL is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer [Misir et al. DOI:10.1038/s41418-022-00948-7]. In hepatocellular carcinoma, it promotes stem-like characteristics and tumor growth via the miR-328-3p/HIF1AN axis under hypoxic conditions [Huang et al. DOI:10.3390/cells11091381]. A study in mice demonstrated that the circCDYL is decreased in myocardial tissues and hypoxia myocardial cells, where it improves cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].