Basic Information

Symbol
circCDYL
RNA Class
circRNA
Alias
Chromodomain Y Like CDYL1 Testis-Specific Chromodomain Y-Like Protein Chromodomain Protein, Y-Like Chromodomain Y-Like Protein Crotonyl-CoA Hydratase CDY-Like, Autosomal DKFZP586C1622 Chromodomain Protein, Y Chromosome-Like EC 2.3.1.48 EC 4.2.1.- CDY-Like
Location (GRCh37)
6:4706393-4955778 UCSC Genome Browser
Location (GRCh38)
6:4706159-4955544
UCSC Genome Browser Search in Marker Scope
Host gene
CDYL
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CDYL_0002900 Intron-Exon-Intron chr6:4864319-4920371 chr6:4864085-4920137 279 nt 0.4014
hsa_CDYL_0003000 Intron-Exon chr6:4867590-4892332 chr6:4867356-4892098 81 nt 0.3951
hsa_CDYL_0003100 Intron-Exon chr6:4867590-4892337 chr6:4867356-4892103 472 nt 0.4703
hsa_CDYL_0003200 Intron-Exon-Intron chr6:4867590-4892613 chr6:4867356-4892379 748 nt 0.5254
hsa_CDYL_0003300 Intron-Exon-Intron chr6:4867590-4894274 chr6:4867356-4894040 63 nt 0.4762
hsa_CDYL_0003400 Intron-Exon chr6:4876591-4892337 chr6:4876357-4892103 23 nt 0.6087
hsa_CDYL_0003500 Intron-Exon chr6:4879239-4892337 chr6:4879005-4892103 443 nt 0.4740
hsa_CDYL_0003600 Intron-Exon-Intron chr6:4879239-4892613 chr6:4879005-4892379 58 nt 0.3966
hsa_CDYL_0003700 Intron-Exon-Intron chr6:4879239-4897442 chr6:4879005-4897208 129 nt 0.3256
hsa_CDYL_0003800 Intron-Exon chr6:4881599-4892337 chr6:4881365-4892103 143 nt 0.4476
Showing 41 to 50 of 115 entries
Forensic Context

A study in humans demonstrated that the circCDYL is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer [Misir et al. DOI:10.1038/s41418-022-00948-7]. In hepatocellular carcinoma, it promotes stem-like characteristics and tumor growth via the miR-328-3p/HIF1AN axis under hypoxic conditions [Huang et al. DOI:10.3390/cells11091381]. A study in mice demonstrated that the circCDYL is decreased in myocardial tissues and hypoxia myocardial cells, where it improves cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].