Basic Information

Symbol
circCDYL
RNA Class
circRNA
Alias
Chromodomain Y Like CDYL1 Testis-Specific Chromodomain Y-Like Protein Chromodomain Protein, Y-Like Chromodomain Y-Like Protein Crotonyl-CoA Hydratase CDY-Like, Autosomal DKFZP586C1622 Chromodomain Protein, Y Chromosome-Like EC 2.3.1.48 EC 4.2.1.- CDY-Like
Location (GRCh37)
6:4706393-4955778 UCSC Genome Browser
Location (GRCh38)
Host gene
CDYL
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CDYL_0003900 Intron-Exon-Intron chr6:4881599-4892613 chr6:4881365-4892379 143 nt 0.4476
hsa_CDYL_0004000 Intron-Exon chr6:4888971-4892337 chr6:4888737-4892103 455 nt 0.4747
hsa_CDYL_0004100 Intron-Exon-Intron chr6:4888971-4892613 chr6:4888737-4892379 64 nt 0.4063
hsa_CDYL_0004200 Intron-Exon chr6:4888976-4892337 chr6:4888742-4892103 59 nt 0.4068
hsa_CDYL_0004700 Intron-Exon chr6:4890489-4892337 chr6:4890255-4892103 586 nt 0.4727
hsa_CDYL_0004400 Intron-Exon-Intron chr6:4890489-4892613 chr6:4890255-4892379 2125 nt 0.4494
hsa_CDYL_0004500 Intron-Exon-Intron chr6:4890489-4897442 chr6:4890255-4897208 250 nt 0.2560
hsa_CDYL_0004800 Intron-Exon-Intron chr6:4890489-4898076 chr6:4890255-4897842 103 nt 0.3883
hsa_CDYL_0004600 Intron-Exon-Intron chr6:4890489-4912360 chr6:4890255-4912126 250 nt 0.2800
hsa_CDYL_0004900 Intron-Exon chr6:4890548-4892337 chr6:4890314-4892103 136 nt 0.5147
Showing 51 to 60 of 115 entries
Forensic Context

A study in humans demonstrated that the circCDYL is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer [Misir et al. DOI:10.1038/s41418-022-00948-7]. In hepatocellular carcinoma, it promotes stem-like characteristics and tumor growth via the miR-328-3p/HIF1AN axis under hypoxic conditions [Huang et al. DOI:10.3390/cells11091381]. A study in mice demonstrated that the circCDYL is decreased in myocardial tissues and hypoxia myocardial cells, where it improves cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].