Basic Information

Symbol
circCDYL
RNA Class
circRNA
Alias
Chromodomain Y Like CDYL1 Testis-Specific Chromodomain Y-Like Protein Chromodomain Protein, Y-Like Chromodomain Y-Like Protein Crotonyl-CoA Hydratase CDY-Like, Autosomal DKFZP586C1622 Chromodomain Protein, Y Chromosome-Like EC 2.3.1.48 EC 4.2.1.- CDY-Like
Location (GRCh37)
6:4706393-4955778 UCSC Genome Browser
Location (GRCh38)
6:4706159-4955544
UCSC Genome Browser Search in Marker Scope
Host gene
CDYL
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CDYL_0005000 Intron-Exon-Intron chr6:4891113-4892613 chr6:4890879-4892379 58 nt 0.3966
hsa_CDYL_0005100 Intron-Exon-Intron chr6:4891500-4892613 chr6:4891266-4892379 1114 nt 0.4964
hsa_CDYL_0005800 Exon-Exon chr6:4891947-4892337 chr6:4891713-4892103 391 nt 0.4859
hsa_CDYL_0006000 Intron-Exon-Intron chr6:4891947-4894274 chr6:4891713-4894040 559 nt 0.4794
hsa_CDYL_0006100 Intron-Exon-Intron chr6:4891947-4896696 chr6:4891713-4896462 478 nt 0.4895
hsa_CDYL_0005600 Intron-Exon-Intron chr6:4891947-4896721 chr6:4891713-4896487 250 nt 0.3920
hsa_CDYL_0006200 Intron-Exon-Intron chr6:4891947-4897442 chr6:4891713-4897208 252 nt 0.4325
hsa_CDYL_0006300 Intron-Exon-Intron chr6:4891947-4906617 chr6:4891713-4906383 107 nt 0.3925
hsa_CDYL_0005700 Intron-Exon-Intron chr6:4891947-4909043 chr6:4891713-4908809 250 nt 0.3920
hsa_CDYL_0006400 Intron-Exon-Intron chr6:4891947-4909184 chr6:4891713-4908950 915 nt 0.5377
Showing 61 to 70 of 115 entries
Forensic Context

A study in humans demonstrated that the circCDYL is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer [Misir et al. DOI:10.1038/s41418-022-00948-7]. In hepatocellular carcinoma, it promotes stem-like characteristics and tumor growth via the miR-328-3p/HIF1AN axis under hypoxic conditions [Huang et al. DOI:10.3390/cells11091381]. A study in mice demonstrated that the circCDYL is decreased in myocardial tissues and hypoxia myocardial cells, where it improves cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].