Basic Information

Symbol
circCDYL
RNA Class
circRNA
Alias
Chromodomain Y Like CDYL1 Testis-Specific Chromodomain Y-Like Protein Chromodomain Protein, Y-Like Chromodomain Y-Like Protein Crotonyl-CoA Hydratase CDY-Like, Autosomal DKFZP586C1622 Chromodomain Protein, Y Chromosome-Like EC 2.3.1.48 EC 4.2.1.- CDY-Like
Location (GRCh37)
6:4706393-4955778 UCSC Genome Browser
Location (GRCh38)
6:4706159-4955544
UCSC Genome Browser Search in Marker Scope
Host gene
CDYL
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CDYL_0006500 Intron-Exon-Intron chr6:4891947-4912360 chr6:4891713-4912126 115 nt 0.3391
hsa_CDYL_0006600 Intron-Exon-Intron chr6:4891947-4912744 chr6:4891713-4912510 164 nt 0.5854
hsa_CDYL_0006700 Intron-Exon-Intron chr6:4891947-4924979 chr6:4891713-4924745 94 nt 0.3723
hsa_CDYL_0005900 Exon-Exon chr6:4891947-4943990 chr6:4891713-4943756 1308 nt 0.4985
hsa_CDYL_0006800 Exon-Exon chr6:4891955-4892613 chr6:4891721-4892379 659 nt 0.5432
hsa_chr6_0550700 Intergenic-Intergenic chr6:4891965-4892324 chr6:4891731-4892090 360 nt 0.4889
hsa_CDYL_0006900 Exon-Exon chr6:4891984-4892613 chr6:4891750-4892379 630 nt 0.5571
hsa_chr6_0550800 Intergenic-Intergenic chr6:4891991-4892324 chr6:4891757-4892090 334 nt 0.5060
hsa_CDYL_0007000 Exon-Exon chr6:4892014-4892337 chr6:4891780-4892103 324 nt 0.5123
hsa_chr6_0550900 Intergenic-Intergenic chr6:4892144-4892324 chr6:4891910-4892090 181 nt 0.4917
Showing 71 to 80 of 115 entries
Forensic Context

A study in humans demonstrated that the circCDYL is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer [Misir et al. DOI:10.1038/s41418-022-00948-7]. In hepatocellular carcinoma, it promotes stem-like characteristics and tumor growth via the miR-328-3p/HIF1AN axis under hypoxic conditions [Huang et al. DOI:10.3390/cells11091381]. A study in mice demonstrated that the circCDYL is decreased in myocardial tissues and hypoxia myocardial cells, where it improves cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].