Basic Information

Symbol
circCDYL
RNA Class
circRNA
Alias
Chromodomain Y Like CDYL1 Testis-Specific Chromodomain Y-Like Protein Chromodomain Protein, Y-Like Chromodomain Y-Like Protein Crotonyl-CoA Hydratase CDY-Like, Autosomal DKFZP586C1622 Chromodomain Protein, Y Chromosome-Like EC 2.3.1.48 EC 4.2.1.- CDY-Like
Location (GRCh37)
6:4706393-4955778 UCSC Genome Browser
Location (GRCh38)
6:4706159-4955544
UCSC Genome Browser Search in Marker Scope
Host gene
CDYL
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
External database
circbank

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CDYL_0007100 Exon-Exon chr6:4892378-4892558 chr6:4892144-4892324 181 nt 0.6464
hsa_CDYL_0007200 Exon-Exon chr6:4892531-4937971 chr6:4892297-4937737 173 nt 0.4855
hsa_CDYL_0007500 Intron-Intron chr6:4894107-4897442 chr6:4893873-4897208 354 nt 0.4407
hsa_CDYL_0007300 Intron-Intron chr6:4894107-4898505 chr6:4893873-4898271 250 nt 0.3880
hsa_CDYL_0007600 Intron-Intron chr6:4894107-4906617 chr6:4893873-4906383 275 nt 0.4364
hsa_CDYL_0007700 Intron-Intron chr6:4894107-4906858 chr6:4893873-4906624 251 nt 0.4104
hsa_CDYL_0007400 Intron-Intron chr6:4894107-4907115 chr6:4893873-4906881 250 nt 0.3440
hsa_CDYL_0007800 Intron-Intron chr6:4894107-4909043 chr6:4893873-4908809 301 nt 0.4684
hsa_CDYL_0007900 Intron-Intron chr6:4894107-4912360 chr6:4893873-4912126 280 nt 0.4821
hsa_CDYL_0008000 Intron-Intron chr6:4894107-4919203 chr6:4893873-4918969 211 nt 0.3791
Showing 81 to 90 of 115 entries
Forensic Context

A study in humans demonstrated that the circCDYL is highly expressed in early stages of hepatocellular carcinoma, bladder cancers, and breast cancer [Misir et al. DOI:10.1038/s41418-022-00948-7]. In hepatocellular carcinoma, it promotes stem-like characteristics and tumor growth via the miR-328-3p/HIF1AN axis under hypoxic conditions [Huang et al. DOI:10.3390/cells11091381]. A study in mice demonstrated that the circCDYL is decreased in myocardial tissues and hypoxia myocardial cells, where it improves cardiac function after acute myocardial infarction [Sema Misir et al. DOI:10.1038/s41418-022-00948-7].