Forensic RNA Knowledge Base

Basic Information

Symbol

circCFH

RNA Class

circRNA

Alias

Complement Factor H ARMS1 ARMD4 FHL1 HUS HF1 HF2 HF Age-Related Maculopathy Susceptibility 1 H Factor 2 (Complement) H Factor 1 (Complement) Beta-1H Adrenomedullin Binding Protein Beta-1-H-Globulin Factor H-Like 1 H Factor 1 Factor H AHUS1 AMBP1 CFHL3 FH

Location (GRCh37)

1:196706605-196712758 UCSC Genome Browser

Location (GRCh38)

1:196737475-196743628

UCSC Genome Browser Search in Marker Scope

Host gene

CFH

Host category

mRNA

Forensic tag(s)

Other applications

External database

circbank

Transcripts

ID	Type	Location (GRCh37)	Location (GRCh38)	Length	GC content
hsa_CFH_0014100	Exon-Exon	chr1:196706605-196712758	chr1:196737475-196743628	714 nt	0.4118

Forensic Context

A review of human hepatocellular carcinoma and hepatoblastoma literature indicates that the circCFH is upregulated and functions as a miRNA sponge for miR-1250-3p, where its silencing decreases cancer cell proliferation, invasion, and viability [Lee et al. DOI:10.1016/j.biopha.2018.12.052].