Basic Information

Symbol
circCHD2
RNA Class
circRNA
Alias
Chromodomain Helicase DNA Binding Protein 2 Chromodomain-Helicase-DNA-Binding Protein 2 ATP-Dependent Helicase CHD2 DKFZp686E01200 DKFZp547I1315 DKFZp781D1727 FLJ38614 CHD-2 EC 3.6.4.- EC 3.6.1 DEE94 EEOC
Location (GRCh37)
15:93428745-93570444 UCSC Genome Browser
Location (GRCh38)
Host gene
CHD2
Host category
mRNA
Forensic tag(s)
Cause of death analysis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CHD2_0004600 Exon-Exon chr15:93444016-93563488 chr15:92900786-93020258 39 nt 0.4103
hsa_CHD2_0004700 Exon-Exon chr15:93444019-93444529 chr15:92900789-92901299 169 nt 0.4201
hsa_CHD2_0004800 Exon-Exon chr15:93444019-93470560 chr15:92900789-92927330 488 nt 0.4734
hsa_CHD2_0004900 Exon-Exon chr15:93444019-93472321 chr15:92900789-92929091 550 nt 0.4800
hsa_CHD2_0005000 Exon-Exon chr15:93444019-93480855 chr15:92900789-92937625 277 nt 0.4332
hsa_CHD2_0005100 Exon-Exon chr15:93444019-93482948 chr15:92900789-92939718 434 nt 0.4608
hsa_CHD2_0005200 Exon-Exon chr15:93444019-93485185 chr15:92900789-92941955 481 nt 0.4387
hsa_CHD2_0005300 Exon-Exon chr15:93444019-93489446 chr15:92900789-92946216 260 nt 0.4385
hsa_CHD2_0005400 Exon-Exon chr15:93444019-93489570 chr15:92900789-92946340 230 nt 0.3565
hsa_CHD2_0005500 Exon-Exon chr15:93444019-93492306 chr15:92900789-92949076 401 nt 0.4813
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Forensic Context

A study in humans demonstrated that the circCHD2 was significantly more abundant in CD14+ monocytes from critically ill patients with sepsis due to community-acquired pneumonia compared to healthy subjects. This circular RNA was resistant to RNase R digestion, confirming its circular nature, and its expression was not induced by ex vivo stimulation of healthy monocytes with bacterial components [Khan et al. DOI:10.1186/s13054-020-03146-4].