Basic Information

Symbol
circCHD2
RNA Class
circRNA
Alias
Chromodomain Helicase DNA Binding Protein 2 Chromodomain-Helicase-DNA-Binding Protein 2 ATP-Dependent Helicase CHD2 DKFZp686E01200 DKFZp547I1315 DKFZp781D1727 FLJ38614 CHD-2 EC 3.6.4.- EC 3.6.1 DEE94 EEOC
Location (GRCh37)
15:93428745-93570444 UCSC Genome Browser
Location (GRCh38)
Host gene
CHD2
Host category
mRNA
Forensic tag(s)
Cause of death analysis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CHD2_0024300 Exon-Exon chr15:93489051-93536228 chr15:92945821-92992998 140 nt 0.5286
hsa_CHD2_0024400 Exon-Exon chr15:93489051-93541851 chr15:92945821-92998621 168 nt 0.5000
hsa_CHD2_0024500 Exon-Exon chr15:93489051-93545547 chr15:92945821-93002317 45 nt 0.3778
hsa_CHD2_0024600 Exon-Exon chr15:93489059-93510743 chr15:92945829-92967513 37 nt 0.3514
hsa_CHD2_0024800 Exon-Exon chr15:93489268-93518180 chr15:92946038-92974950 1379 nt 0.4394
hsa_CHD2_0024900 Exon-Exon chr15:93489268-93524687 chr15:92946038-92981457 1868 nt 0.4438
hsa_CHD2_0025700 Intron-Intron chr15:93489478-93490703 chr15:92946248-92947473 160 nt 0.3813
hsa_CHD2_0025800 Intron-Exon-Intron chr15:93489478-93492484 chr15:92946248-92949254 125 nt 0.4480
hsa_CHD2_0025900 Intron-Exon-Intron chr15:93489478-93492538 chr15:92946248-92949308 93 nt 0.3226
hsa_CHD2_0026000 Intron-Exon-Intron chr15:93489478-93493661 chr15:92946248-92950431 329 nt 0.3860
Showing 221 to 230 of 472 entries
Forensic Context

A study in humans demonstrated that the circCHD2 was significantly more abundant in CD14+ monocytes from critically ill patients with sepsis due to community-acquired pneumonia compared to healthy subjects. This circular RNA was resistant to RNase R digestion, confirming its circular nature, and its expression was not induced by ex vivo stimulation of healthy monocytes with bacterial components [Khan et al. DOI:10.1186/s13054-020-03146-4].