Basic Information
Symbol
circCHD2
RNA Class
circRNA
Alias
Chromodomain Helicase DNA Binding Protein 2
Chromodomain-Helicase-DNA-Binding Protein 2
ATP-Dependent Helicase CHD2
DKFZp686E01200
DKFZp547I1315
DKFZp781D1727
FLJ38614
CHD-2
EC 3.6.4.-
EC 3.6.1
DEE94
EEOC
Location (GRCh37)
15:93428745-93570444
UCSC Genome Browser
Location (GRCh38)
15:92885515-93027214
Host gene
CHD2
Host category
mRNA
Forensic tag(s)
Cause of death analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_CHD2_0025300 | Intron-Exon-Intron | chr15:93489478-93494830 | chr15:92946248-92951600 | 250 nt | 0.2880 |
| hsa_CHD2_0026100 | Intron-Exon-Intron | chr15:93489478-93496803 | chr15:92946248-92953573 | 93 nt | 0.3226 |
| hsa_CHD2_0026200 | Intron-Exon-Intron | chr15:93489478-93498742 | chr15:92946248-92955512 | 96 nt | 0.3542 |
| hsa_CHD2_0025400 | Intron-Exon-Intron | chr15:93489478-93510743 | chr15:92946248-92967513 | 250 nt | 0.3040 |
| hsa_CHD2_0026300 | Intron-Exon-Intron | chr15:93489478-93524687 | chr15:92946248-92981457 | 224 nt | 0.3884 |
| hsa_CHD2_0026400 | Intron-Exon-Intron | chr15:93489478-93536228 | chr15:92946248-92992998 | 255 nt | 0.4078 |
| hsa_CHD2_0025500 | Intron-Exon-Intron | chr15:93489478-93540633 | chr15:92946248-92997403 | 250 nt | 0.2920 |
| hsa_CHD2_0025600 | Intron-Exon-Intron | chr15:93489478-93541491 | chr15:92946248-92998261 | 250 nt | 0.3480 |
| hsa_CHD2_0026600 | Intron-Exon-Intron | chr15:93491977-93494495 | chr15:92948747-92951265 | 2519 nt | 0.3855 |
| hsa_CHD2_0027600 | Intron-Exon-Intron | chr15:93492182-93493661 | chr15:92948952-92950431 | 236 nt | 0.4110 |
Showing 231 to 240 of 472 entries
Forensic Context
A study in humans demonstrated that the circCHD2 was significantly more abundant in CD14+ monocytes from critically ill patients with sepsis due to community-acquired pneumonia compared to healthy subjects. This circular RNA was resistant to RNase R digestion, confirming its circular nature, and its expression was not induced by ex vivo stimulation of healthy monocytes with bacterial components [Khan et al. DOI:10.1186/s13054-020-03146-4].