Basic Information

Symbol
circCHD2
RNA Class
circRNA
Alias
Chromodomain Helicase DNA Binding Protein 2 Chromodomain-Helicase-DNA-Binding Protein 2 ATP-Dependent Helicase CHD2 DKFZp686E01200 DKFZp547I1315 DKFZp781D1727 FLJ38614 CHD-2 EC 3.6.4.- EC 3.6.1 DEE94 EEOC
Location (GRCh37)
15:93428745-93570444 UCSC Genome Browser
Location (GRCh38)
Host gene
CHD2
Host category
mRNA
Forensic tag(s)
Cause of death analysis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CHD2_0032400 Intron-Intron chr15:93507073-93507236 chr15:92963843-92964006 164 nt 0.4024
hsa_CHD2_0032600 Intron-Exon-Intron chr15:93508472-93528903 chr15:92965242-92985673 176 nt 0.5341
hsa_CHD2_0032500 Intron-Exon-Intron chr15:93508472-93536228 chr15:92965242-92992998 250 nt 0.4320
hsa_CHD2_0033300 Exon-Exon chr15:93510555-93515157 chr15:92967325-92971927 189 nt 0.4392
hsa_CHD2_0032900 Exon-Exon chr15:93510555-93515647 chr15:92967325-92972417 505 nt 0.4218
hsa_CHD2_0033400 Exon-Exon chr15:93510555-93518180 chr15:92967325-92974950 261 nt 0.4598
hsa_CHD2_0033000 Exon-Exon chr15:93510555-93521613 chr15:92967325-92978383 727 nt 0.4525
hsa_CHD2_0033500 Exon-Exon chr15:93510555-93522513 chr15:92967325-92979283 189 nt 0.4392
hsa_CHD2_0033100 Exon-Exon chr15:93510555-93524141 chr15:92967325-92980911 973 nt 0.4502
hsa_CHD2_0033600 Exon-Exon chr15:93510555-93524687 chr15:92967325-92981457 99 nt 0.3737
Showing 291 to 300 of 472 entries
Forensic Context

A study in humans demonstrated that the circCHD2 was significantly more abundant in CD14+ monocytes from critically ill patients with sepsis due to community-acquired pneumonia compared to healthy subjects. This circular RNA was resistant to RNase R digestion, confirming its circular nature, and its expression was not induced by ex vivo stimulation of healthy monocytes with bacterial components [Khan et al. DOI:10.1186/s13054-020-03146-4].