Basic Information
Symbol
circCHD2
RNA Class
circRNA
Alias
Chromodomain Helicase DNA Binding Protein 2
Chromodomain-Helicase-DNA-Binding Protein 2
ATP-Dependent Helicase CHD2
DKFZp686E01200
DKFZp547I1315
DKFZp781D1727
FLJ38614
CHD-2
EC 3.6.4.-
EC 3.6.1
DEE94
EEOC
Location (GRCh37)
15:93428745-93570444
UCSC Genome Browser
Location (GRCh38)
15:92885515-93027214
Host gene
CHD2
Host category
mRNA
Forensic tag(s)
Cause of death analysis
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_CHD2_0053100 | Exon-Exon | chr15:93570047-93570207 | chr15:93026817-93026977 | 161 nt | 0.5093 |
| hsa_CHD2_0053200 | Exon-Exon | chr15:93570047-93570316 | chr15:93026817-93027086 | 270 nt | 0.4556 |
Showing 471 to 472 of 472 entries
Forensic Context
A study in humans demonstrated that the circCHD2 was significantly more abundant in CD14+ monocytes from critically ill patients with sepsis due to community-acquired pneumonia compared to healthy subjects. This circular RNA was resistant to RNase R digestion, confirming its circular nature, and its expression was not induced by ex vivo stimulation of healthy monocytes with bacterial components [Khan et al. DOI:10.1186/s13054-020-03146-4].