Basic Information

Symbol
circCHD2
RNA Class
circRNA
Alias
Chromodomain Helicase DNA Binding Protein 2 Chromodomain-Helicase-DNA-Binding Protein 2 ATP-Dependent Helicase CHD2 DKFZp686E01200 DKFZp547I1315 DKFZp781D1727 FLJ38614 CHD-2 EC 3.6.4.- EC 3.6.1 DEE94 EEOC
Location (GRCh37)
15:93428745-93570444 UCSC Genome Browser
Location (GRCh38)
Host gene
CHD2
Host category
mRNA
Forensic tag(s)
Cause of death analysis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CHD2_0036400 Intron-Exon-Intron chr15:93521378-93536228 chr15:92978148-92992998 1104 nt 0.4728
hsa_CHD2_0037500 Exon-Exon chr15:93521464-93522513 chr15:92978234-92979283 299 nt 0.4983
hsa_CHD2_0037600 Exon-Exon chr15:93521464-93528903 chr15:92978234-92985673 836 nt 0.4701
hsa_CHD2_0037700 Exon-Exon chr15:93521464-93536228 chr15:92978234-92992998 1018 nt 0.4764
hsa_CHD2_0038900 Exon-Exon chr15:93522365-93555674 chr15:92979135-93012444 1965 nt 0.4550
hsa_CHD2_0039500 Exon-Exon chr15:93524045-93534747 chr15:92980815-92991517 579 nt 0.4525
hsa_CHD2_0039600 Exon-Exon chr15:93524045-93540633 chr15:92980815-92997403 1009 nt 0.4519
hsa_CHD2_0042100 Exon-Exon chr15:93528728-93552553 chr15:92985498-93009323 1355 nt 0.4716
hsa_CHD2_0042800 Exon-Exon chr15:93534706-93536228 chr15:92991476-92992998 182 nt 0.5055
hsa_CHD2_0042900 Exon-Exon chr15:93534706-93565392 chr15:92991476-93022162 250 nt 0.3600
Showing 51 to 60 of 472 entries
Forensic Context

A study in humans demonstrated that the circCHD2 was significantly more abundant in CD14+ monocytes from critically ill patients with sepsis due to community-acquired pneumonia compared to healthy subjects. This circular RNA was resistant to RNase R digestion, confirming its circular nature, and its expression was not induced by ex vivo stimulation of healthy monocytes with bacterial components [Khan et al. DOI:10.1186/s13054-020-03146-4].