Basic Information

Symbol
circCHD2
RNA Class
circRNA
Alias
Chromodomain Helicase DNA Binding Protein 2 Chromodomain-Helicase-DNA-Binding Protein 2 ATP-Dependent Helicase CHD2 DKFZp686E01200 DKFZp547I1315 DKFZp781D1727 FLJ38614 CHD-2 EC 3.6.4.- EC 3.6.1 DEE94 EEOC
Location (GRCh37)
15:93428745-93570444 UCSC Genome Browser
Location (GRCh38)
Host gene
CHD2
Host category
mRNA
Forensic tag(s)
Cause of death analysis
External database

Transcripts

ID Type Location (GRCh37) Location (GRCh38) Length GC content
hsa_CHD2_0050800 Exon-Exon chr15:93552375-93552553 chr15:93009145-93009323 179 nt 0.5307
hsa_CHD2_0050900 Exon-Exon chr15:93552375-93555674 chr15:93009145-93012444 279 nt 0.4659
hsa_CHD2_0051000 Exon-Exon chr15:93552375-93558139 chr15:93009145-93014909 493 nt 0.4888
hsa_CHD2_0051100 Exon-Exon chr15:93552375-93563488 chr15:93009145-93020258 740 nt 0.5014
hsa_CHD2_0051200 Exon-Exon chr15:93552405-93555658 chr15:93009175-93012428 233 nt 0.4635
hsa_CHD2_0051800 Exon-Exon chr15:93557926-93558139 chr15:93014696-93014909 214 nt 0.5187
hsa_CHD2_0051900 Exon-Exon chr15:93557926-93563488 chr15:93014696-93020258 461 nt 0.5228
hsa_CHD2_0001300 Intergenic-Exon chr15:93428745-93499879 chr15:92885515-92956649 139 nt 0.3237
hsa_CHD2_0000800 Intergenic-Exon chr15:93428745-93510743 chr15:92885515-92967513 250 nt 0.2880
hsa_CHD2_0001400 Intergenic-Exon chr15:93428745-93536228 chr15:92885515-92992998 225 nt 0.3333
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Forensic Context

A study in humans demonstrated that the circCHD2 was significantly more abundant in CD14+ monocytes from critically ill patients with sepsis due to community-acquired pneumonia compared to healthy subjects. This circular RNA was resistant to RNase R digestion, confirming its circular nature, and its expression was not induced by ex vivo stimulation of healthy monocytes with bacterial components [Khan et al. DOI:10.1186/s13054-020-03146-4].