Basic Information
Symbol
circCHP1
RNA Class
circRNA
Alias
Calcineurin Like EF-Hand Protein 1
CHP
SLC9A1BP
Sid470p
P22
P24
EF-Hand Calcium-Binding Domain-Containing Protein P22
Calcineurin B Homologous Protein 1
Calcineurin Homologous Protein
Calcium-Binding Protein CHP
Calcium-Binding Protein P22
Calcineurin B-Like Protein
Calcium Binding Protein P22
SLC9A1 Binding Protein
Calcineurin B Homolog
SPAX9
Location (GRCh37)
15:41535865-41571087
UCSC Genome Browser
Location (GRCh38)
15:41243667-41278889
Host gene
CHP1
Host category
mRNA
Forensic tag(s)
Sudden cardiac death diagnosis
Other applications
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_CHP1_0001100 | Exon-Exon | chr15:41535865-41571087 | chr15:41243667-41278889 | 538 nt | 0.4777 |
Forensic Context
A study in mice demonstrated that the circCHP1 counteracts hypoxia-induced ATP depletion and apoptotic death in cardiomyocytes via the miR-15b/Arl2 axis and alleviates hypoxic injury in HaCaT cells via the miR-449a/NF-κB and PI3K/AKT pathways [Huang et al. DOI:10.3390/cells11091381]. A review of circular RNAs in human diseases highlights their roles as biomarkers and therapeutic targets across various conditions, including cancer, cardiovascular, and neurological disorders, with studies in human tissues and biofluids demonstrating differential expression patterns associated with disease progression and treatment response [Lee et al. DOI:10.1016/j.biopha.2018.12.052].