Forensic RNA Knowledge Base

Basic Information

Symbol

circCNOT6L

RNA Class

circRNA

Alias

CCR4-NOT Transcription Complex Subunit 6 Like Ccr4b Carbon Catabolite Repressor Protein 4 Homolog B CCR4-NOT Transcription Complex Subunit 6-Like DKFZp434K098 CCR4-NOT Transcription Complex, Subunit 6-Like EC 3.1.13.4 CCR4B

Location (GRCh37)

4:78634541-78740544 UCSC Genome Browser

Location (GRCh38)

4:77713387-77819390

UCSC Genome Browser Search in Marker Scope

Host gene

CNOT6L

Host category

mRNA

Forensic tag(s)

Drug abuse diagnoses

External database

circbank

Transcripts

ID	Type	Location (GRCh37)	Location (GRCh38)	Length	GC content
hsa_chr4_0586800	Intergenic-Intergenic	chr4:78731751-78734957	chr4:77810597-77813803	250 nt	0.2560
hsa_chr4_0586900	Intergenic-Intergenic	chr4:78737171-78737526	chr4:77816017-77816372	356 nt	0.2528

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Forensic Context

A study in rats demonstrated that the circCNOT6L was identified as a putative heroin-associated biomarker via microarray analysis in the orbitofrontal cortex following heroin self-administration, but subsequent validation by quantitative PCR did not show significant regulation in either male or female rats [Floris et al. DOI:10.3390/ijms23031453].