Forensic RNA Knowledge Base

Basic Information

Symbol

circCSRP1

RNA Class

circRNA

Alias

Cysteine And Glycine Rich Protein 1 CSRP D1S181E CYRP Cysteine And Glycine-Rich Protein 1 Epididymis Luminal Protein 141 Cysteine-Rich Protein 1 HEL-141 CRP1 CRP Epididymis Secretory Sperm Binding Protein Epididymis Secretory Protein Li 286 LIM-Domain Protein HEL-S-286

Location (GRCh37)

1:201452658-201459472 UCSC Genome Browser

Location (GRCh38)

1:201483530-201490344

UCSC Genome Browser Search in Marker Scope

Host gene

CSRP1

Host category

mRNA

Forensic tag(s)

Drug abuse diagnoses

External database

circbank

Transcripts

ID	Type	Location (GRCh37)	Location (GRCh38)	Length	GC content
hsa_CSRP1_0000300	Exon-Exon	chr1:201452658-201459472	chr1:201483530-201490344	1653 nt	0.5529

Forensic Context

A review of hypoxia-induced circular RNAs in human diseases, including studies in human and mouse models, identified numerous circRNAs with roles in cancer progression, therapeutic resistance, angiogenesis, and energy metabolism [Huang et al. DOI:10.3390/cells11091381]. A study in SH-SY5Y cells demonstrated that the circCSRP1 is down-regulated upon methamphetamine treatment and functions as a sponge for miR-129-1-3p, implicating it in dopaminergic apoptosis [Xu et al. DOI:10.1007/S10571-023-01323-X].