Basic Information
Symbol
circDYNC1H1
RNA Class
circRNA
Alias
Dynein Cytoplasmic 1 Heavy Chain 1
DHC1
Dnchc1
CMT2O
DNCH1
DNECL
HL-3
DNCL
P22
Dynein, Cytoplasmic, Heavy Polypeptide 1
Cytoplasmic Dynein 1 Heavy Chain 1
Dynein Heavy Chain, Cytosolic
DYHC
Cytoplasmic Dynein Heavy Chain 1
KIAA0325
CDCBM13
SMALED1
DHC1a
Location (GRCh37)
14:102468874-102469302
UCSC Genome Browser
Location (GRCh38)
14:102002537-102002965
Host gene
DYNC1H1
Host category
mRNA
Forensic tag(s)
Forensic psychiatry evaluation
Cause of death analysis
Sudden death from respiratory system disease
External database
Transcripts
| ID | Type | Location (GRCh37) | Location (GRCh38) | Length | GC content |
|---|---|---|---|---|---|
| hsa_DYNC1H1_0017800 | Exon-Exon | chr14:102468874-102469302 | chr14:102002537-102002965 | 341 nt | 0.4839 |
Forensic Context
A study in mice demonstrated that circDYNC1H1 is highly expressed in neurons and brain tissue, playing crucial roles in brain development and Alzheimer’s disease [Sema Misir et al. DOI:10.1038/s41418-022-00948-7]. A study in humans identified hsa_circRNA_101286 as an exonic circRNA significantly up-regulated in the lung tissues and plasma of patients with sepsis-induced acute respiratory distress syndrome (ARDS) compared to non-ARDS controls [Guo et al. DOI:10.1016/j.lfs.2021.119566].