Basic Information

Symbol
hsa-let-7a-2
RNA class
miRNA miRNA hairpin
Alias
MIRLET7A2 MicroRNA Let-7a-2 Hsa-Let-7a-2-3p Hsa-Let-7a-5p Hsa-Let-7a-2 MIRNLET7A2 Hsa-Let-7-P1d_pre MIMAT0000062 MIMAT0010195 MI0000061 Let-7a-2 LET7A2
Location (GRCh38)
11:122146522-122146593
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-let-7a-2
Sequence length
72 nt
GC content
0.4028

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-25.20 kcal/mol
Thermodynamic ensemble
Free energy: -26.39 kcal/mol
Frequency: 0.1451
Diversity: 5.07
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in mice demonstrated that the let-7a-2 is a member of the abundantly expressed let-7 family in liver tissue, and deep sequencing identified 48 differentially expressed miRNAs, including 21 novel miRNAs, in response to ionizing radiation-induced liver injury [Lu et al. DOI:10.1002/cbin.10627].