Basic Information

Symbol
hsa-mir-411
RNA class
miRNA miRNA hairpin
Alias
MIR411 MicroRNA 411 Hsa-MiR-411-3p Hsa-MiR-411-5p Hsa-Mir-411 MIRN411 Hsa-Mir-154-P13-V1_pre Hsa-Mir-154-P13-V2_pre MIMAT0004813 MIMAT0003329 MI0003675 Mir-411
Location (GRCh38)
14:101023325-101023420
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Individual identification Mechanical injury analysis Wound age identification Drug abuse diagnoses
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-411
Sequence length
96 nt
GC content
0.4688

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-30.60 kcal/mol
Thermodynamic ensemble
Free energy: -31.93 kcal/mol
Frequency: 0.1154
Diversity: 5.77
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((((..(((.(.((((.((((((...((((((((.........).)))))))...)))))).)))).).))))))))))..............
Thermodynamic Ensemble Prediction
(((((((..(((.(.((((.((((((.,.((((((({.........).)))))))...)))))).)))).).))))))))))..............
Forensic Context

A study in humans demonstrated that the mir-411 is downregulated 24 hours post-injury in skin wounds compared to unwounded skin [Siu et al. DOI:10.1111/wrr.13100]. A study in mice demonstrated that silencing synaptic the mir-411 reduces voluntary alcohol consumption [Zhu et al. DOI:10.1007/S00221-022-06305-X]. In human hematopoietic stem cells from cord blood, the mir-411 was among miRNAs with the highest expression in fraternal twins and showed low differences in expression between both fraternal and identical twin pairs [Ajami et al. DOI:10.22074/cellj.2019.5683].