Basic Information

Symbol
hsa-mir-423
RNA class
miRNA miRNA hairpin
Alias
MIR423 Hsa-Mir-423 MIRN423 Hsa-Mir-423_pre MIMAT0004748 MIMAT0001340 MI0001445 Mir-423
Location (GRCh38)
17:30117079-30117172
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Tissue/body fluid identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-423
Sequence length
94 nt
GC content
0.5213

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-48.80 kcal/mol
Thermodynamic ensemble
Free energy: -49.13 kcal/mol
Frequency: 0.5841
Diversity: 1.16
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
....(((((((.((((((((((((..(((.((((.(((((.........))))))))).)))...)))))))))))).))))))).........
Forensic Context

A study in humans demonstrated that hsa-miR-423-5p was significantly increased (2.897-fold) in plasma-derived exosomes from acute myocardial infarction patients compared to controls using next-generation sequencing [Kim et al. DOI:10.3390/ijms25179619]. A study in humans systematically evaluated 18 small RNA reference genes in forensically relevant body fluids (venous blood, menstrual blood, saliva, semen, and vaginal secretions) from the Chinese Han population, identifying the mir-423 as an applicable and stable reference gene with high amplification efficiency, ranking among the top stable genes and having the lowest comprehensive ranking value in venous blood and vaginal secretions [Wang et al. DOI:10.1002/elps.202000058].