Basic Information

Symbol
hsa-mir-4258
RNA class
miRNA miRNA hairpin
Alias
MIR4258 MicroRNA 4258 Hsa-Mir-4258 MIMAT0016879 Hsa-MiR-4258 MI0015857
Location (GRCh38)
1:212077613-212077685
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4258
Sequence length
91 nt
GC content
0.6813

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-54.20 kcal/mol
Thermodynamic ensemble
Free energy: -55.49 kcal/mol
Frequency: 0.1235
Diversity: 10.40
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((((((((((((((((..((((.(((((((((((..........))))))))).....)).)))).))))...)))))))))).)))).
Thermodynamic Ensemble Prediction
(((((((((((((({{{(,,((((.(((((((((((..........))))))))}....,),.)))).})))...)))))))))).)))).
Forensic Context

A study in healthy human volunteers demonstrated that the mir-4258 increased 3.01-fold in serum following recreational alcohol consumption, with this change being part of a broader dynamic response where 265 microRNAs showed significant increases [Ten Berg et al. DOI:10.1080/1354750X.2018.1499128].