Basic Information

Symbol
hsa-miR-4258
RNA class
miRNA mature miRNA
Alias
hsa-miR-4258 MIR4258 MicroRNA 4258
Location (GRCh38)
-
Forensic tag(s)
Drug abuse diagnoses
External database

Sequence & Structure

Transcript ID
hsa-miR-4258
Sequence length
17 nt
GC content
0.8235

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-54.20 kcal/mol
Thermodynamic ensemble
Free energy: -55.49 kcal/mol
Frequency: 0.1235
Diversity: 10.40
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in healthy human volunteers demonstrated that the miR-4258 increased 3.01-fold in serum following recreational alcohol consumption, with this change being part of a broader dynamic response where 265 microRNAs showed significant increases [Ten Berg et al. DOI:10.1080/1354750X.2018.1499128].