Basic Information

Symbol
hsa-mir-4284
RNA class
miRNA miRNA hairpin
Alias
MIR4284 MicroRNA 4284 Hsa-Mir-4284 Hsa-MiR-4284 MIMAT0016915 MI0015893 Mir-4284
Location (GRCh38)
7:151433489-151433639
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Individual identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4284
Sequence length
81 nt
GC content
0.5679

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-24.20 kcal/mol
Thermodynamic ensemble
Free energy: -27.21 kcal/mol
Frequency: 0.0076
Diversity: 14.92
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((((..(((((((....((((((.((...((((....))))...))...))))).)....))))))).))))).))..
Thermodynamic Ensemble Prediction
{((((((.{(((((((....{(((((.((...((({....})))...)}...))))).)....))))))).)))))},}..
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns in human skin tissue and cells post-burn and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the mir-4284 was differentially expressed across four pairs of monozygotic twins in blood samples, establishing its role as a biomarker for distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].