Basic Information
Symbol
hsa-miR-4284
RNA class
miRNA
mature miRNA
Alias
hsa-miR-4284
MIR4284
MicroRNA 4284
Location (GRCh38)
-
Forensic tag(s)
Wound age identification
Individual identification
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-24.20 kcal/mol
Thermodynamic ensemble
Free energy:
-27.21 kcal/mol
Frequency:
0.0076
Diversity:
14.92
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(((((((..(((((((....((((((.((...((((....))))...))...))))).)....))))))).))))).))..
Thermodynamic Ensemble Prediction
{((((((.{(((((((....{(((((.((...((({....})))...)}...))))).)....))))))).)))))},}..
Forensic Context
A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific expression patterns in human skin tissue and cells post-burn and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that the miR-4284 was differentially expressed across four pairs of monozygotic twins in blood samples, establishing its role as a biomarker for distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].