Basic Information
Symbol
hsa-miR-4287
RNA class
miRNA
mature miRNA
Alias
hsa-miR-4287
MIR4287
MicroRNA 4287
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-27.40 kcal/mol
Thermodynamic ensemble
Free energy:
-28.21 kcal/mol
Frequency:
0.2673
Diversity:
5.55
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..((((((..(((((((.(((((.(((((((((...)))))).......))))))).).)))))))....))))))..
Thermodynamic Ensemble Prediction
..((((((..(((((((.(((((,(((((((((...)))))).....,.))})))).).)))))))....))))))..
Forensic Context
A study in humans demonstrated that the miR-4287 was identified as a differentially expressed microRNA shared across two pairs of monozygotic twins in blood samples, suggesting its potential role in distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003]. The investigation, which analyzed miRNA expression profiles via microarray and validated findings with qRT-PCR, confirmed differential expression patterns for selected miRNAs, indicating that such biomarkers could be applicable for forensic identification of monozygotic twins.