Basic Information

Symbol
hsa-mir-4298
RNA class
miRNA miRNA hairpin
Alias
MIR4298 MicroRNA 4298 Hsa-Mir-4298 MIMAT0016852 Hsa-MiR-4298 MI0015830
Location (GRCh38)
1:248826377-248826443
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Individual identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4298
Sequence length
73 nt
GC content
0.5616

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-24.80 kcal/mol
Thermodynamic ensemble
Free energy: -25.47 kcal/mol
Frequency: 0.3387
Diversity: 6.09
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((((..(((((..(((((..((..((((((....)))))).....))...)))))...)).)))..))))..
Thermodynamic Ensemble Prediction
.{(((..(((((..(((((..((..((((((....)))))).....))...)))))...)).)))..))))..
Forensic Context

A review of human studies identified 197 miRNAs associated with wound healing, burn wound healing, and scarring, with specific miRNAs showing altered expression in human skin tissue samples post-burn, during wound healing, and in hypertrophic scar tissue [Siu et al. DOI:10.1111/wrr.13100]. A study in humans demonstrated that miRNA expression profiles from blood samples can distinguish monozygotic twins, with 545 differentially expressed miRNAs identified across 18 twin pairs, including the mir-4298 which was shared across two pairs [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].