Basic Information

Symbol
hsa-mir-431
RNA class
miRNA miRNA hairpin
Alias
MIR431 MicroRNA 431 Hsa-MiR-431-3p Hsa-Mir-431 MIRN431 Hsa-Mir-431_pre Hsa-MiR-431-5p MIMAT0004757 MIMAT0001625 MI0001721 MiRNA431 Mir-431
Location (GRCh38)
15:80841978-80842073
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification Mechanical injury analysis
External database
HGNC NCBI Ensembl OMIM miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-431
Sequence length
114 nt
GC content
0.5877

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-43.40 kcal/mol
Thermodynamic ensemble
Free energy: -45.29 kcal/mol
Frequency: 0.0466
Diversity: 41.47
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...((.(((((.(((((((.((((((((((.((.(.((((((((........)))....))))).).)).)))))))))).))))))).)))))))..................
Thermodynamic Ensemble Prediction
.,{(({,(({({((((((..,,||||||||.{{.{,{|||||,,....||||}},..}}}})))}|{||{|||||}|||,..))})))}))))))...................
Forensic Context

A study in human skin epidermal stem cells demonstrated that the mir-431-5p was upregulated 6 hours post-burn in heat-shocked cells compared to controls [Siu et al. DOI:10.1111/wrr.13100]. A study in non-human primates (Macaca mulatta) demonstrated that the mir-431-5p was differentially expressed in plasma after whole-thorax lung irradiation prior to dexamethasone intervention [Rogers et al. DOI:10.1667/RADE-20-00031.1].