Basic Information
Symbol
hsa-miR-4317
RNA class
miRNA
mature miRNA
Alias
hsa-miR-4317
MIR4317
MicroRNA 4317
Location (GRCh38)
-
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-16.30 kcal/mol
Thermodynamic ensemble
Free energy:
-17.65 kcal/mol
Frequency:
0.1114
Diversity:
12.47
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
....,((((((((((,,|((((((((........)))))))),}....}))))))}.})......
Forensic Context
A study in humans with coronary artery disease identified the miR-4317 as a biomarker for recurrent myocardial infarction risk, where it was downregulated in whole blood of patients with recurrent MI compared to those without, remaining significant after false-discovery rate correction (FDR <0.1) in a replication cohort, though it was not significantly different in plasma samples [Onuoha et al. DOI:10.1111/cts.13307].