Basic Information

Symbol
hsa-mir-4433a
RNA class
miRNA miRNA hairpin
Alias
MIR4433A MicroRNA 4433a Hsa-Mir-4433 MicroRNA 4433 MIR4433 Hsa-MiR-4433a-5p Hsa-MiR-4433a-3p Hsa-Mir-4433a MIMAT0020956 MIMAT0018949 MI0016773
Location (GRCh38)
2:64340759-64340839
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis Individual identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4433a
Sequence length
81 nt
GC content
0.5185

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-57.60 kcal/mol
Thermodynamic ensemble
Free energy: -59.57 kcal/mol
Frequency: 0.0407
Diversity: 8.57
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
.((((((((((.(((((((((((((((((((((,.,({........))))))))))))))))))))))).)))))))))).
Forensic Context

A study in humans identified the mir-4433a-3p as significantly upregulated in whole blood of patients with recurrent myocardial infarction compared to stable coronary artery disease patients after percutaneous coronary intervention, with this differential expression remaining significant after false discovery rate correction [Onuoha et al. DOI:10.1111/cts.13307]. In a separate forensic investigation, the mir-4433a-3p was identified as a differentially expressed microRNA shared across two pairs of monozygotic twins, suggesting its potential role in distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].