Forensic Context

A study in humans identified the miR-4433a-3p as significantly upregulated in whole blood of patients with recurrent myocardial infarction compared to stable coronary artery disease patients after percutaneous coronary intervention, with this differential expression remaining significant after false discovery rate correction [Onuoha et al. DOI:10.1111/cts.13307]. In a separate forensic investigation, the miR-4433a-3p was identified as a differentially expressed microRNA shared across two pairs of monozygotic twins, suggesting its potential role in distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].