Basic Information

Symbol
hsa-mir-1236
RNA class
miRNA miRNA hairpin
Alias
MIR1236 MicroRNA 1236 Hsa-MiR-1236-3p Hsa-Mir-1236 MIRN1236 Hsa-MiR-1236-5p MIMAT0005591 MIMAT0022945 MI0006326
Location (GRCh38)
6:31956839-31956940
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-1236
Sequence length
102 nt
GC content
0.5490

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-36.40 kcal/mol
Thermodynamic ensemble
Free energy: -39.41 kcal/mol
Frequency: 0.0076
Diversity: 27.26
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(.(((.((((((((((..((..(((.....((.(.(((((((.....)))).))).).)).((((...)))).)))....))..)))))).)))).))))..
Thermodynamic Ensemble Prediction
{.(((.((((((((((..((({{{,...,,({.{.(((((((.....)))).))),).)}.{(((...)))).,,,..,.))},))))))}}))).)))}..
Forensic Context

A study in mice and human prostate epithelial cells demonstrated that cadmium exposure increased the mir-1236 level, which functioned as a sponge for miRNA-1236-3p to stimulate the SHH signaling pathway, promoting epithelial-mesenchymal transition and prostatic fibrosis [Huang et al. DOI:10.1002/Jat.4436]. A review of human skin tissue identified 197 miRNAs with altered expression post-burn and during wound healing and scarring, with five key miRNAs altering fibroproliferative markers and cell behaviors [Siu et al. DOI:10.1111/wrr.13100].