Basic Information

Symbol
hsa-mir-4435-1
RNA class
miRNA miRNA hairpin
Alias
MIR4435-1 MicroRNA 4435-1 Hsa-Mir-4435-1 Hsa-MiR-4435 MIMAT0018951 Mir-4435-1 MI0016775 hsa-mir-4435
Location (GRCh38)
1:9967381-9967458
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4435-1
Sequence length
80 nt
GC content
0.5500

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-29.20 kcal/mol
Thermodynamic ensemble
Free energy: -30.27 kcal/mol
Frequency: 0.1755
Diversity: 5.63
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((((.....(((((.(((.((((((...(((.((((.....)))))))...)))))))))....))))).....)))).
Thermodynamic Ensemble Prediction
.((((.....(((((.(((.((((((.,.(((.((((.....))))))).,.)))))))))....))))).....)))).
Forensic Context

A study in humans identified the mir-4435 as a potential biomarker, finding it was significantly higher in plaque rupture patients than in plaque erosion patients within a replication cohort, though it was lower in ST-segment elevation myocardial infarction patients compared to healthy controls [Li et al. DOI:10.1016/j.ygeno.2020.11.019]. A study in humans demonstrated that the mir-4435 is a potential biomarker for venous blood identification in forensic body fluid analysis, as it is listed among specific markers for this fluid type [Zhiyong Liu et al. DOI:10.1007/s00414-025-03656-2].