Basic Information

Symbol
hsa-mir-4446
RNA class
miRNA miRNA hairpin
Alias
MIR4446 MicroRNA 4446 Hsa-MiR-4446-3p Hsa-Mir-4446 Hsa-MiR-4446-5p MIMAT0019233 MIMAT0018965 MI0016789 Mir-4446
Location (GRCh38)
14:104677694-104677749
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden unexpected death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4446
Sequence length
67 nt
GC content
0.5373

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-26.00 kcal/mol
Thermodynamic ensemble
Free energy: -26.75 kcal/mol
Frequency: 0.2964
Diversity: 6.66
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
.((((((((.((.((((((..,((({((.............)))))).)))))).)).)))))))).
Forensic Context

A study in humans investigating circulating and tissue miRNAs in a case of sudden unexpected death in epilepsy (SUDEP) found that the mir-4446-3p showed no significant expression differences between the SUDEP case and control cases in plasma and hippocampal tissue [De Matteis et al. DOI:10.1016/J.Legalmed.2017.12.003].