Basic Information

Symbol
hsa-miR-4449
RNA class
miRNA mature miRNA
Alias
hsa-miR-4449 MIR4449 MicroRNA 4449
Location (GRCh38)
-
Forensic tag(s)
Cause of death analysis
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-4449
Sequence length
22 nt
GC content
0.8182

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-47.50 kcal/mol
Thermodynamic ensemble
Free energy: -48.50 kcal/mol
Frequency: 0.1984
Diversity: 6.15
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
.{{.{.((((((((((((..((((((((((....)))))))))).))))))).))))),....)).
Forensic Context

A study in human myocardial autopsy specimens from septic patients demonstrated that the miR-4449 was up-regulated in septic hearts compared to non-septic controls [Pasi Lehto et al. DOI:10.1038/s41598-024-81114-6].