Basic Information

Symbol
hsa-mir-4454
RNA class
miRNA miRNA hairpin
Alias
MIR4454 MicroRNA 4454 Hsa-Mir-4454 Hsa-MiR-4454 MIMAT0018976 MI0016800
Location (GRCh38)
4:163093574-163093628
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4454
Sequence length
55 nt
GC content
0.5636

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-14.20 kcal/mol
Thermodynamic ensemble
Free energy: -14.68 kcal/mol
Frequency: 0.4626
Diversity: 5.20
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans identified the mir-4454 as a top upregulated microRNA in the plasma of patients with acute myocardial infarction compared to non-AMI controls, classifying it as a diagnostic biomarker for this condition [Zhong et al. DOI:10.1002/jcla.23099].