Basic Information
Symbol
hsa-miR-4454
RNA class
miRNA
mature miRNA
Alias
hsa-miR-4454
MIR4454
MicroRNA 4454
Location (GRCh38)
-
Forensic tag(s)
Sudden cardiac death diagnosis
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-14.20 kcal/mol
Thermodynamic ensemble
Free energy:
-14.68 kcal/mol
Frequency:
0.4626
Diversity:
5.20
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context
A study in humans identified the miR-4454 as a top upregulated microRNA in the plasma of patients with acute myocardial infarction compared to non-AMI controls, classifying it as a diagnostic biomarker for this condition [Zhong et al. DOI:10.1002/jcla.23099].