Basic Information

Symbol
hsa-mir-4458
RNA class
miRNA miRNA hairpin
Alias
MIR4458 MicroRNA 4458 Hsa-Mir-4458 Hsa-MiR-4458 MIMAT0018980 MI0016804 Mir-4458
Location (GRCh38)
5:8460925-8460999
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4458
Sequence length
75 nt
GC content
0.4533

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-26.80 kcal/mol
Thermodynamic ensemble
Free energy: -27.69 kcal/mol
Frequency: 0.2352
Diversity: 6.26
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in human vascular endothelial cells demonstrated that the mir-4458 was significantly downregulated (fold change 11.09) in exosomes derived from cells subjected to heat stroke temperature conditions, identifying it as a potential noninvasive biomarker for heat stroke [Chen et al. DOI:10.12659/MSM.909983].