Forensic Context

A study in mice and human prostate epithelial cells demonstrated that cadmium exposure increased the mir-1236 level, which functioned as a sponge for miRNA-1236-3p to stimulate the SHH signaling pathway, promoting epithelial-mesenchymal transition and prostatic fibrosis [Huang et al. DOI:10.1002/Jat.4436]. A review of human skin tissue identified 197 miRNAs with altered expression post-burn and during wound healing and scarring, with five key miRNAs altering fibroproliferative markers and cell behaviors [Siu et al. DOI:10.1111/wrr.13100].