Basic Information

Symbol
hsa-miR-448
RNA class
miRNA mature miRNA
Alias
hsa-miR-448 MIR448 MicroRNA 448
Location (GRCh38)
-
Forensic tag(s)
Mechanical injury analysis
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-448
Sequence length
22 nt
GC content
0.4091

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-51.20 kcal/mol
Thermodynamic ensemble
Free energy: -53.11 kcal/mol
Frequency: 0.0454
Diversity: 11.57
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((.(((((((.(.((((((((((((.(((.(((((....(((((.((......)).))))).....))))).))))))))))))))).).))))))).))...........
Thermodynamic Ensemble Prediction
((.(((((((.(.((((((((((({,(((.(((((....(((((.{(,.....,},))))),....))))).))))))))))))))).).))))))).))...........
Forensic Context

A review of human studies identified the miR-448 as upregulated in chronic mild traumatic brain injury patients when measured in exosomes from serum [Li et al. DOI:10.1016/j.neuint.2023.105643].