Basic Information

Symbol
hsa-miR-449c-5p
RNA class
miRNA mature miRNA
Alias
hsa-miR-449c MIR449C MicroRNA 449c
Location (GRCh38)
-
Forensic tag(s)
Cause of death analysis Tissue/body fluid identification
External database
miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-miR-449c-5p
Sequence length
25 nt
GC content
0.5200
Forensic Context

A study in mice demonstrated that the mir-449c was identified as an up-regulated known miRNA in thymus tissue following whole-body ionizing radiation exposure [Chen et al. DOI:10.1080/09553002.2016.1207821]. A review summarizing radiation biomarkers noted that the mir-449c is specifically expressed in spleen tissue and also in the kidney and small intestine, indicating its tissue-specific distribution [Jia et al. DOI:10.3389/fcell.2022.861451].