Basic Information

Symbol
hsa-mir-4496
RNA class
miRNA miRNA hairpin
Alias
MIR4496 MicroRNA 4496 Hsa-Mir-4496 Hsa-MiR-4496 MIMAT0019031 MI0016858
Location (GRCh38)
12:108635810-108635870
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Individual identification
External database
HGNC NCBI Ensembl miRBase RNAcentral

Sequence & Structure

Transcript ID
hsa-mir-4496
Sequence length
61 nt
GC content
0.4426

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-15.60 kcal/mol
Thermodynamic ensemble
Free energy: -16.98 kcal/mol
Frequency: 0.1071
Diversity: 3.98
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans identified the mir-4496 as differentially expressed in hypertrophic scar tissue compared to normal skin, where it was downregulated [Siu et al. DOI:10.1111/wrr.13100]. In a separate forensic investigation in humans, the mir-4496 was found to be differentially expressed within monozygotic twin pairs, being shared across three pairs of twins, which demonstrates its potential utility for distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].