Basic Information
Symbol
hsa-miR-4496
RNA class
miRNA
mature miRNA
Alias
hsa-miR-4496
MIR4496
MicroRNA 4496
Location (GRCh38)
-
Forensic tag(s)
Tissue/body fluid identification
Individual identification
External database
Sequence & Structure
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-15.60 kcal/mol
Thermodynamic ensemble
Free energy:
-16.98 kcal/mol
Frequency:
0.1071
Diversity:
3.98
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context
A study in humans identified the miR-4496 as differentially expressed in hypertrophic scar tissue compared to normal skin, where it was downregulated [Siu et al. DOI:10.1111/wrr.13100]. In a separate forensic investigation in humans, the miR-4496 was found to be differentially expressed within monozygotic twin pairs, being shared across three pairs of twins, which demonstrates its potential utility for distinguishing genetically identical individuals [Xiao et al. DOI:10.1016/j.fsigen.2019.05.003].